BRAF mutant PD-L1 positive metastatic musculoskeletal lesions from primary lung adenocarcinoma treated with combination vemurafenib and pembrolizumab: a case report

Although a rare occurrence and known to have a poor prognosis, B-Raf mutation positive programmed death ligand 1 overexpressed lung adenocarcinoma presenting with metastatic musculoskeletal lesions can respond favorably to a combination immune checkpoint inhibitor and BRAF inhibitor medication.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2024-09-28
DOI
https://doi.org/10.1186/s13256-024-04773-z
Primary Topic
Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

BRAF mutant PD-L1 positive metastatic musculoskeletal lesions from primary lung adenocarcinoma treated with combination vemurafenib and pembrolizumab: a case report

Corazon A. Ngelangel, Fatoumata Sy
Journal of Medical Case Reports
Cancer Diagnosis and Treatment
article

BRAF mutant PD-L1 positive metastatic musculoskeletal lesions from primary lung adenocarcinoma treated with combination vemurafenib and pembrolizumab: a case report

Corazon A. Ngelangel, Fatoumata Sy
article en

Abstract

Although a rare occurrence and known to have a poor prognosis, B-Raf mutation positive programmed death ligand 1 overexpressed lung adenocarcinoma presenting with metastatic musculoskeletal lesions can respond favorably to a combination immune checkpoint inhibitor and BRAF inhibitor medication.

Journal of Medical Case ReportsVol. 18(1)
Asian Hospital and Medical Center (PH), Philippine General Hospital (PH)
Good health and well-being
Openalex Percentile: Top 70%
Cancer Diagnosis and Treatment
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