Methotrexate-induced leukoencephalopathy presenting as acute-onset limb weakness in a child: a case report

This case report describes a patient with rapidly progressing methotrexate-induced leukoencephalopathy following oral methotrexate. It highlights that the risk of neurotoxicity persists even with the oral use of methotrexate; therefore, the prescribers should be vigilant of this uncommon side effect.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2024-09-28
DOI
https://doi.org/10.1186/s13256-024-04824-5
Citations
1
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
0.54
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article

Methotrexate-induced leukoencephalopathy presenting as acute-onset limb weakness in a child: a case report

Shobhavi Randeny, Sachith Mettananda, Hashan Pathiraja, Gayathri de Abrew et al.
1 citations
Journal of Medical Case Reports
Acute Lymphoblastic Leukemia research
0.54
article

Methotrexate-induced leukoencephalopathy presenting as acute-onset limb weakness in a child: a case report

Shobhavi Randeny, Sachith Mettananda, Hashan Pathiraja, Gayathri de Abrew, Sanjaya Fernando, Linushika de Silva
article en
1 citations

Abstract

This case report describes a patient with rapidly progressing methotrexate-induced leukoencephalopathy following oral methotrexate. It highlights that the risk of neurotoxicity persists even with the oral use of methotrexate; therefore, the prescribers should be vigilant of this uncommon side effect.

Journal of Medical Case ReportsVol. 18(1)
University of Kelaniya (LK), Colombo North Teaching Hospital (LK)
Good health and well-being
Openalex Percentile: Top 28%
Acute Lymphoblastic Leukemia research
0.54
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