Management of anti-melanoma differentiation-associated gene 5 antibody-induced refractory dermatomyositis complicated by interstitial pneumonia using tofacitinib and its outcomes: a case report

The patient with anti-melanoma differentiation-associated gene 5 antibody-related rapidly progressive interstitial lung disease, whose disease was difficult to control after the administration of triple immunosuppressive therapy (steroids, tacrolimus, and cyclophosphamide), showed good response with tofacitinib. Unfortunately, the patient died of invasive pulmonary aspergillosis owing to severe immunosuppression; thus, the signs of complications should be promptly detected.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2024-09-28
DOI
https://doi.org/10.1186/s13256-024-04793-9
Citations
1
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.39
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article

Management of anti-melanoma differentiation-associated gene 5 antibody-induced refractory dermatomyositis complicated by interstitial pneumonia using tofacitinib and its outcomes: a case report

Hirotaka Nishikiori, Yuichiro Asai, Yuki Mori, Hirofumi Chiba et al.
1 citations
Journal of Medical Case Reports
Inflammatory Myopathies and Dermatomyositis
0.39
article

Management of anti-melanoma differentiation-associated gene 5 antibody-induced refractory dermatomyositis complicated by interstitial pneumonia using tofacitinib and its outcomes: a case report

Hirotaka Nishikiori, Yuichiro Asai, Yuki Mori, Hirofumi Chiba, Michiko Hosaka, Takafumi Yorozuya, Shun Kondoh, Atsushi Saito, Takumi Nishimaki, Tatsuru Ishikawa, Taku Hatakeyama, Yui Imai, Tomoyuki Takahashi
article en
1 citations

Abstract

The patient with anti-melanoma differentiation-associated gene 5 antibody-related rapidly progressive interstitial lung disease, whose disease was difficult to control after the administration of triple immunosuppressive therapy (steroids, tacrolimus, and cyclophosphamide), showed good response with tofacitinib. Unfortunately, the patient died of invasive pulmonary aspergillosis owing to severe immunosuppression; thus, the signs of complications should be promptly detected.

Journal of Medical Case ReportsVol. 18(1)
Sapporo Medical University (JP), Muroran Institute of Technology (JP)
Good health and well-being
Openalex Percentile: Top 34%
Inflammatory Myopathies and Dermatomyositis
0.39
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