Dose escalation in radical radio(chemo)therapy for cervical and upper thoracic esophageal cancer with 3DCRT/IMRT (ChC&UES): a multicenter retrospective study
HD radiotherapy benefits cervical but not upper thoracic ESCA, while increasing bone marrow suppression risk. Further dose escalating (≥ 63 Gy) doesn't improve survival but enhances ORR.
Authors
- Junqiang Chen (ORCID: https://orcid.org/0000-0003-1484-9382)
- Xiaohan Zhao (ORCID: https://orcid.org/0000-0002-3467-9467)
- Yuanji Xu (ORCID: https://orcid.org/0000-0002-7194-0433)
- Yatian Liu (ORCID: https://orcid.org/0000-0001-7803-0494)
- Xiaojie Xia (ORCID: https://orcid.org/0000-0002-6486-7557)
- Chunyue Gai
- Xin Wang (ORCID: https://orcid.org/0000-0003-1753-2786)
- Shuchai Zhu (ORCID: https://orcid.org/0000-0003-0199-7431)
- Kuaile Zhao (ORCID: https://orcid.org/0000-0003-1271-2278)
- Hongmei Gao (ORCID: https://orcid.org/0000-0002-1795-3380)
- Pu-Dong Qian (ORCID: https://orcid.org/0000-0003-3188-2088)
- Hesong Wang (ORCID: https://orcid.org/0000-0003-2659-8787)
- Wencheng Zhang (ORCID: https://orcid.org/0000-0002-9416-6540)
- Wenbin Shen (ORCID: https://orcid.org/0000-0002-5166-5745)
- Wei Huang (ORCID: https://orcid.org/0000-0001-9849-3883)
- Xiaolin Ge
- Chen-Gang Weng
Institutions
- Hebei Medical University (CN)
- Fujian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
- National Cancer Center (US)
- Fudan University Shanghai Cancer Center (CN)
- Fourth Hospital of Hebei Medical University (CN)
- First Hospital of Shijiazhuang (CN)
- Jiangsu Cancer Hospital (CN)
- Fujian Provincial Cancer Hospital (CN)
- Jiangsu Province Hospital (CN)
- Shandong First Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1186/s13014-024-02521-7
- Citations
- 3
- Primary Topic
- Esophageal Cancer Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.72