Deciphering the role of sphingolipid metabolism in the immune microenvironment and prognosis of esophageal cancer via single-cell sequencing and bulk data analysis
This study integrates single-cell and transcriptomic data to provide a reliable prognostic model associated with sphingolipid metabolism and to inform immunotherapy and pharmacotherapy for ESCC at the genetic level. The findings have significant implications for precision therapy in esophageal cancer.
Authors
- Ping Zhao (ORCID: https://orcid.org/0000-0001-5168-0307)
- Siqi Wei (ORCID: https://orcid.org/0000-0002-2603-8248)
- Rongzhang He (ORCID: https://orcid.org/0000-0003-4890-4060)
- Xiufang Luo
- Tianchi Zhang (ORCID: https://orcid.org/0000-0002-7909-5596)
- Haotian Lai
- Linjuan Du
- Jing Tang (ORCID: https://orcid.org/0000-0003-3100-1842)
- Guobin Tang
- Jie Liu
Institutions
- Southwest Medical University (CN)
- Taiyuan Central Hospital (CN)
- Dazhou Central Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1007/s12672-024-01379-1
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.24