Oxygen matters: Unraveling the role of oxygen in the neuronal response to cisplatin
These results underscore the critical role of oxygen in neuronal culture, particularly in studying compounds where neuronal damage is mechanistically linked to oxidative stress. Even at identical doses of evaluated neurotoxic drugs, distinct cellular phenotypic fates can emerge, impacting translatability to the in vivo setting.
Authors
- Montse Alemany
- Aina Calls (ORCID: https://orcid.org/0000-0002-8233-456X)
- Esther Udina (ORCID: https://orcid.org/0000-0003-1954-8562)
- Vı́ctor J. Yuste (ORCID: https://orcid.org/0000-0001-5322-9261)
- Oriol Casanovas (ORCID: https://orcid.org/0000-0002-4298-3995)
- Estefanía Contreras (ORCID: https://orcid.org/0000-0002-8645-2790)
- Jordi Bruna (ORCID: https://orcid.org/0000-0001-6895-5047)
- Xavier Navarro (ORCID: https://orcid.org/0000-0001-9849-902X)
- Jose Crugeiras (ORCID: https://orcid.org/0009-0005-8478-2939)
Institutions
- Universitat Autònoma de Barcelona (ES)
- Bellvitge University Hospital (ES)
- Biomedical Research Networking Center on Neurodegenerative Diseases (ES)
- Institut d'Investigació Biomédica de Bellvitge (ES)
- Institut Català d'Oncologia (ES)
Publication Details
- Journal
- Journal of the Peripheral Nervous System
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1111/jns.12659
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Instituto de Salud Carlos III