Single-Cell Transcriptomic Analysis Reveals Dynamic Cellular Processes in Corneal Epithelium During Wound Healing in Cynomolgus Monkeys
Our study represents the first comprehensive exploration of the detailed transcriptome profile of individual corneal cells during the wound healing process in nonhuman primates. We demonstrate the intricate mechanisms involved in corneal healing and provide a promising avenue for potential therapies in corneal wound healing.
Authors
- Qi Dai (ORCID: https://orcid.org/0000-0003-2675-6511)
- Yingfeng Zheng (ORCID: https://orcid.org/0000-0002-0914-7864)
- Xiaolin Liang (ORCID: https://orcid.org/0000-0002-5479-4067)
- Qikai Zhang (ORCID: https://orcid.org/0009-0009-6454-9549)
- Yuheng Lin (ORCID: https://orcid.org/0000-0002-0796-0130)
- Zhuoxing Shi (ORCID: https://orcid.org/0000-0001-7463-4979)
- Zhong Liu (ORCID: https://orcid.org/0000-0003-3067-1967)
- Dongliang Wang (ORCID: https://orcid.org/0000-0003-0605-5726)
- Ming Zhou (ORCID: https://orcid.org/0000-0003-2545-1134)
- Li Sun (ORCID: https://orcid.org/0009-0003-8140-9667)
- Shurui Ke
- Qiuling Hu (ORCID: https://orcid.org/0009-0004-5627-776X)
- Chaoyang Wang
Institutions
- Zhejiang Sci-Tech University (CN)
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1167/iovs.65.11.43
- Citations
- 7
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- State Key Laboratory of Ophthalmology