Feature-based detection of breast cancer using convolutional neural network and feature engineering

Breast cancer (BC) is a prominent cause of female mortality on a global scale. Recently, there has been growing interest in utilizing blood and tissue-based biomarkers to detect and diagnose BC, as this method offers a non-invasive approach. To improve the classification and prediction of BC using large biomarker datasets, several machine-learning techniques have been proposed. In this paper, we present a multi-stage approach that consists of computing new features and then sorting them into an input image for the ResNet50 neural network. The method involves transforming the original values into normalized values based on their membership in the Gaussian distribution of healthy and BC samples of each feature. To test the effectiveness of our proposed approach, we employed the Coimbra and Wisconsin datasets. The results demonstrate efficient performance improvement, with an accuracy of 100% and 100% using the Coimbra and Wisconsin datasets, respectively. Furthermore, the comparison with existing literature validates the reliability and effectiveness of our methodology, where the normalized value can reduce the misclassified samples of ML techniques because of its generality.