Ascorbic acid 2‐glucoside improves survival, quality, and fertility of frozen‐thawed C57Bl/6J and C57Bl/6N mouse spermatozoa
This newly improved protocol shows potential for reanimating cryopreserved GEMMs stored in mouse biobanks and international repositories, such as the European Mouse Mutant Archive (EMMA). This can serve as a pivotal tool in fulfilling the 3Rs mission (replacement, reduction, and refinement), promoting ethical and humane research practices.
Authors
- Ferdinando Scavizzi (ORCID: https://orcid.org/0000-0002-4483-6753)
- Marcello Raspa (ORCID: https://orcid.org/0000-0002-3437-2430)
- Renata Paoletti (ORCID: https://orcid.org/0000-0001-8551-8711)
Institutions
- National Research Council (IT)
Publication Details
- Journal
- Andrology
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1111/andr.13768
- Primary Topic
- Sperm and Testicular Function
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- INFRAFRONTIER