Identification of an active fraction of Kangfuxin in the treatment of periodontitis in a rat model
We identified a potent anti-inflammatory fraction (50% ethanol fraction of the n-butanol extract) of Kangfuxin for periodontitis treatment. This fraction suppressed the activity of the PI3K-AKT-mTOR signalling pathway in periodontitis samples. Further research is needed to isolate and characterise the specific bioactive compounds within this fraction.
Authors
- Qiyan Li
- Yanli Tang
- Hui Guo (ORCID: https://orcid.org/0000-0002-4649-5876)
- Jie Pan
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Folia Histochemica et Cytobiologica
- Published
- 2024-09-27
- DOI
- https://doi.org/10.5603/fhc.101230
- Citations
- 2
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Kunming Medical University
- Yunnan Provincial Science and Technology Department