A novel case of reactive perforating collagenosis in a patient with cutaneous infiltration of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma
Reactive perforating collagenosis (RPC) is a cutaneous disorder that has rarely been associated with haematological malignancies. We present the case of a 47-year-old man with a 6-month history of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma (AITL) who was undergoing chemotherapy and had an extremely pruritic, papular eruption that had worsened over the past 7 months. Skin biopsy findings revealed RPC. He was treated with triamcinolone cream and hydroxyzine alongside his chemotherapy; this resolved his symptoms. This patient’s case offers a unique clinicopathological presentation of RPC in the setting of AITL in the skin and demonstrates the importance of a dermatologist's management of cutaneous disorders in patients with cancer to improve their quality of life.
Authors
- Rachael Chacko
- Michael Chapman (ORCID: https://orcid.org/0000-0003-4424-0156)
- Shaofeng Yan (ORCID: https://orcid.org/0000-0001-9654-2100)
- Gabrielle E. Duprat
- Alicia T. Dagrosa (ORCID: https://orcid.org/0000-0002-2347-5602)
- Payal C Shah
Institutions
- Dartmouth College (US)
- Dartmouth Hospital (GB)
- Dartmouth Health (US)
Publication Details
- Journal
- Clinical and Experimental Dermatology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1093/ced/llae346
- Citations
- 1
- Primary Topic
- Dermatological and Skeletal Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.55