A novel case of reactive perforating collagenosis in a patient with cutaneous infiltration of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma

Reactive perforating collagenosis (RPC) is a cutaneous disorder that has rarely been associated with haematological malignancies. We present the case of a 47-year-old man with a 6-month history of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma (AITL) who was undergoing chemotherapy and had an extremely pruritic, papular eruption that had worsened over the past 7 months. Skin biopsy findings revealed RPC. He was treated with triamcinolone cream and hydroxyzine alongside his chemotherapy; this resolved his symptoms. This patient’s case offers a unique clinicopathological presentation of RPC in the setting of AITL in the skin and demonstrates the importance of a dermatologist's management of cutaneous disorders in patients with cancer to improve their quality of life.

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Publication Details

Journal
Clinical and Experimental Dermatology
Published
2024-09-26
DOI
https://doi.org/10.1093/ced/llae346
Citations
1
Primary Topic
Dermatological and Skeletal Disorders
Type
article
Field-Weighted Citation Impact
0.55
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article

A novel case of reactive perforating collagenosis in a patient with cutaneous infiltration of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma

Rachael Chacko, Michael Chapman, Shaofeng Yan, Gabrielle E. Duprat et al.
1 citations
Clinical and Experimental Dermatology
Dermatological and Skeletal Disorders
0.55
article

A novel case of reactive perforating collagenosis in a patient with cutaneous infiltration of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma

Rachael Chacko, Michael Chapman, Shaofeng Yan, Gabrielle E. Duprat, Alicia T. Dagrosa, Payal C Shah
article en
1 citations

Abstract

Reactive perforating collagenosis (RPC) is a cutaneous disorder that has rarely been associated with haematological malignancies. We present the case of a 47-year-old man with a 6-month history of Epstein–Barr virus-positive angioimmunoblastic T-cell lymphoma (AITL) who was undergoing chemotherapy and had an extremely pruritic, papular eruption that had worsened over the past 7 months. Skin biopsy findings revealed RPC. He was treated with triamcinolone cream and hydroxyzine alongside his chemotherapy; this resolved his symptoms. This patient’s case offers a unique clinicopathological presentation of RPC in the setting of AITL in the skin and demonstrates the importance of a dermatologist's management of cutaneous disorders in patients with cancer to improve their quality of life.

Clinical and Experimental DermatologyVol. 50(3)
Dartmouth College (US), Dartmouth Hospital (GB), Dartmouth Health (US)
No poverty
Openalex Percentile: Top 26%
Dermatological and Skeletal Disorders
0.55
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