Population pharmacokinetic and dose–response models of nepadutant, a selective antagonist of the NK<sub>2</sub> receptors, in infants with colic

Population pharmacokinetic and dose-response models were successfully developed characterizing the available nepadutant pharmacokinetics and duration of crying and fussing data in infants.

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Publication Details

Journal
British Journal of Clinical Pharmacology
Published
2024-09-26
DOI
https://doi.org/10.1111/bcp.16230
Primary Topic
Infant Health and Development
Type
article
Field-Weighted Citation Impact
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Population pharmacokinetic and dose–response models of nepadutant, a selective antagonist of the NK2 receptors, in infants with colic

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Population pharmacokinetic and dose–response models of nepadutant, a selective antagonist of the NK2 receptors, in infants with colic

Siv Jönsson, E. Niclas Jonsson, Alessia Tagliavini, Andrea Pellacani, Elisa Borella, Chiara Piana, Sibylle Koletzko, Salim Bouchène, Mats O. Karlsson, Katharina Werkstetter, Angela Capriati, Paolo Mazzei
article en

Abstract

Population pharmacokinetic and dose-response models were successfully developed characterizing the available nepadutant pharmacokinetics and duration of crying and fussing data in infants.

British Journal of Clinical PharmacologyVol. 91(2)
Menarini Group (Italy) (IT), University of Warmia and Mazury in Olsztyn (PL), Ludwig-Maximilians-Universität München (DE), UCB Pharma (Belgium) (BE)
Good health and well-being
Openalex Percentile: Top 71%
Infant Health and Development
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