Myocardial oxygen handling and metabolic function of ex-situ perfused human hearts from circulatory death donors
Hearts on normothermic ESHP receive excessive MDO<sub>2</sub>, due to high <i>P</i>O<sub>2</sub> and CBF, while the MVO<sub>2</sub> is relatively low. Thus, CBF and <i>P</i>O<sub>2</sub> can potentially be lowered. Furthermore, Δ<i>P</i>O<sub>2</sub> could serve as additional marker of metabolic function under these hyperoxic circumstances. The adenosine infusion rate might predict post-transplantation ECMO requirement.
Authors
- Pieter C. van de Woestijne (ORCID: https://orcid.org/0000-0003-0826-7837)
- Jorik H. Amesz (ORCID: https://orcid.org/0000-0002-0305-1271)
- Mark F.A. Bierhuizen (ORCID: https://orcid.org/0000-0002-3689-1699)
- Sanne J.J. Langmuur (ORCID: https://orcid.org/0000-0003-2880-947X)
- Jelena Sjatskig (ORCID: https://orcid.org/0000-0003-2360-0853)
- Dwight Dumay
- Olivier C. Manintveld (ORCID: https://orcid.org/0000-0002-2202-7314)
- Dirk Jan Duncker (ORCID: https://orcid.org/0000-0003-2836-2241)
- Yannick J.H.J. Taverne (ORCID: https://orcid.org/0000-0002-1030-2198)
- Lisa E Sluijter
Institutions
- Erasmus MC (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- JHLT Open
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1016/j.jhlto.2024.100159
- Citations
- 4
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 2.76