Severity of respiratory syncytial virus compared with SARS-CoV-2 and influenza among hospitalised adults ≥65 years

Among patients unvaccinated for influenza or SARS-CoV-2, those with RSV had similar or lower risk of pneumonia [vs. influenza: RR= 0.91 (95% Confidence Interval: 0.72-1.16); vs. SARS-CoV-2: 0.81 (0.67-0.98)], ICU admission [vs. influenza: 0.93 (0.41-2.08); vs. SARS-CoV-2: 1.10 (0.61-1.99)] and mortality [vs. influenza: 0.64 (0.32-1.28); vs. SARS-CoV-2: 0.56 (0.30-1.04)]. Among the vaccinated, results were largely similar except for a higher risk of ICU admission with RSV [vs. influenza: 2.13(1.16-3.89); vs. SARS-CoV-2: 1.83 (1.02-3.28)] CONCLUSIONS: RSV presented similar or lower intrinsic severity than influenza or SARS-CoV2. Among vaccinated patients, RSV was associated to higher ICU-admission, suggesting the potential for preventive RSV vaccination.

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Publication Details

Journal
Journal of Infection
Published
2024-09-26
DOI
https://doi.org/10.1016/j.jinf.2024.106292
Citations
11
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
4.25
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article

Severity of respiratory syncytial virus compared with SARS-CoV-2 and influenza among hospitalised adults ≥65 years

María Isabel Barranco Boada, María del Carmen García‐Rodríguez, Silvia Galindo, Luis Javier Viloria Raymundo et al.
11 citations
Journal of Infection
Respiratory viral infections research
4.25
article

Severity of respiratory syncytial virus compared with SARS-CoV-2 and influenza among hospitalised adults ≥65 years

María Isabel Barranco Boada, María del Carmen García‐Rodríguez, Silvia Galindo, Luis Javier Viloria Raymundo, María Victoria García Rivera, Violeta Ramos Marín, Susana Monge, Luca Basile, Daniel Castrillejo, Ana Fernández Ibáñez, Amparo Larrauri, Olaia Pérez‐Martínez, Jaume Giménez Durán, Virtudes Gallardo García, Virginia Álvarez Río, Nieves López González‐Coviella, Carmen Quiñones Rubio, Miriam García Vázquez, Mercedes Belén Rumayor Zarzuelo, Ana Lameiras Azevedo, José Luis Mayordomo, Lorena Vega-Piris
article en
11 citations

Abstract

Among patients unvaccinated for influenza or SARS-CoV-2, those with RSV had similar or lower risk of pneumonia [vs. influenza: RR= 0.91 (95% Confidence Interval: 0.72-1.16); vs. SARS-CoV-2: 0.81 (0.67-0.98)], ICU admission [vs. influenza: 0.93 (0.41-2.08); vs. SARS-CoV-2: 1.10 (0.61-1.99)] and mortality [vs. influenza: 0.64 (0.32-1.28); vs. SARS-CoV-2: 0.56 (0.30-1.04)]. Among the vaccinated, results were largely similar except for a higher risk of ICU admission with RSV [vs. influenza: 2.13(1.16-3.89); vs. SARS-CoV-2: 1.83 (1.02-3.28)] CONCLUSIONS: RSV presented similar or lower intrinsic severity than influenza or SARS-CoV2. Among vaccinated patients, RSV was associated to higher ICU-admission, suggesting the potential for preventive RSV vaccination.

Journal of InfectionVol. 89(5)
Andalusian Health Service (ES), Government of Spain (ES), Instituto de Salud Carlos III (ES), Generalitat Valenciana (ES), Directorate of Health (IS), Ministry of Health (ES), Centro Nacional de Epidemiología (ES), Instituto de Arqueología-Mérida (ES), Junta de Castilla y León (ES), Health Research Institute of the Balearic Islands (ES), Hospital General Universitario De Valencia (ES), Servicio de Salud de Castilla La Mancha (ES), Gobierno de La Rioja (ES)
Good health and well-being
Openalex Percentile: Top 5%
Respiratory viral infections research
4.25
DOIOpen Access PDFOpenAlex
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