Ex vivo modelling of cardiac injury identifies ferroptosis-related pathways as a potential therapeutic avenue for translational medicine
Our findings highlight the potential of targeting ferroptosis-related pathways and metallothioneins as a promising strategy for the treatment of heart disease.
Authors
- Andreas Pich (ORCID: https://orcid.org/0000-0001-8444-0940)
- Filippo Perbellini (ORCID: https://orcid.org/0000-0003-1540-2777)
- Thomas Thum (ORCID: https://orcid.org/0000-0003-4360-1511)
- Angelika Pfanne
- Arjang Ruhparwar (ORCID: https://orcid.org/0000-0003-2725-9912)
- F. Ius (ORCID: https://orcid.org/0000-0002-8084-3360)
- Florian J. G. Waleczek (ORCID: https://orcid.org/0009-0006-9455-9412)
- Marco Bentele
- Naisam Abbas (ORCID: https://orcid.org/0000-0002-3633-2934)
- Christopher Werlein (ORCID: https://orcid.org/0000-0002-7694-4257)
- Natalie Weber (ORCID: https://orcid.org/0000-0002-2302-1045)
- Jan Fiedler (ORCID: https://orcid.org/0000-0002-8855-2883)
- Maria C. Jordan (ORCID: https://orcid.org/0000-0001-5272-2185)
- Maximilian Fuchs (ORCID: https://orcid.org/0000-0002-8099-9541)
- Susanne Neumüller
- Angelika Stucki-Koch
- Sophie Linke
- W. D. Korte
- Annette Just
Institutions
- Medizinische Hochschule Hannover (DE)
- Fraunhofer Institute for Toxicology and Experimental Medicine (DE)
Publication Details
- Journal
- Journal of Molecular and Cellular Cardiology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1016/j.yjmcc.2024.09.012
- Citations
- 8
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 3.35
Funders
- European Commission
- Deutsche Forschungsgemeinschaft
- Medizinischen Hochschule Hannover
- European Research Council