Computed Tomography of the Head Before Lumbar Puncture in Adults With Suspected Meningitis in High–HIV Prevalence Settings
Patients who had a CT had delays to diagnostic LP and initiation of appropriate treatment; although treatment delays were associated with increased mortality, our observational study could not demonstrate a causal association between delays in diagnosis and treatment introduced by CT and mortality.
Authors
- Daniel Grint (ORCID: https://orcid.org/0000-0001-8001-6544)
- Wallace T. Miller (ORCID: https://orcid.org/0000-0001-7403-9969)
- Samuel Ensor (ORCID: https://orcid.org/0000-0001-8456-9576)
- Hannah E Barton
- Madisa Mine
- Ronan Doyle (ORCID: https://orcid.org/0000-0001-5001-1945)
- David A. Goldfarb (ORCID: https://orcid.org/0000-0003-0835-9504)
- Mark W. Tenforde (ORCID: https://orcid.org/0000-0002-8702-8393)
- Leah A. Owen (ORCID: https://orcid.org/0000-0003-3802-3868)
- Keatlaretse Siamisang
- Tshepo Botho Leeme (ORCID: https://orcid.org/0000-0002-6153-4693)
- Ponego Ponatshego (ORCID: https://orcid.org/0009-0006-7549-8300)
- Kwana Lechiile (ORCID: https://orcid.org/0000-0001-6691-1905)
- Ikanyeng Rulaganyang
- Ezekiel Gwakuba
- James Milburn (ORCID: https://orcid.org/0000-0001-9885-6103)
- Kebatshabile Ngoni (ORCID: https://orcid.org/0000-0002-2763-712X)
- Thandi Milton
- Rachita Suresh (ORCID: https://orcid.org/0009-0002-3317-179X)
- Joseph N Jarvis (ORCID: https://orcid.org/0000-0003-1459-5554)
- Kaelo K. Seatla (ORCID: https://orcid.org/0000-0002-2190-2842)
- Margaret Mokomane (ORCID: https://orcid.org/0000-0002-4406-3594)
- Tichaona Machiya (ORCID: https://orcid.org/0009-0002-8839-3998)
- Gerald Boitshepo
- William James Hurt
- Christopher G. Williams (ORCID: https://orcid.org/0000-0003-3893-3124)
Institutions
- University of British Columbia (CA)
- University of Botswana (BW)
- London School of Hygiene & Tropical Medicine (GB)
- Botswana Open University (BW)
- National Public Health Laboratory (NP)
- Princess Margaret Hospital (HK)
- Botswana Harvard AIDS Institute Partnership (BW)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1093/ofid/ofae565
- Citations
- 3
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 1.03
Funders
- University of Pennsylvania
- London School of Hygiene and Tropical Medicine
- Government of the United Kingdom
- National Institute for Health and Care Research
- Department of Health and Social Care
- Medical Research Council