Molecular genetic characterization of myeloid neoplasms with idic(X)(q13) and i(X)(q10)
The breakpoints of idic(X)(q13) are within a 200kbp. i(X)(q10) in our study turned out to be a cryptic idic(X)(p11) aberration, reported for the first time here. <i>TET2</i>, <i>SF3B1</i>, <i>ASXL1</i>, or <i>SRSF2</i> were highly prevalent in patients with idic(X)(q13)/i(X)(q10) abnormalities and were often associated with a worse prognosis.
Authors
- Francesca Micci (ORCID: https://orcid.org/0000-0002-2194-556X)
- Gunhild Trøen
- Andrea Lenartova (ORCID: https://orcid.org/0000-0001-8166-4404)
- Signe Spetalen (ORCID: https://orcid.org/0000-0002-2426-5316)
- Ioannis Panagopoulos (ORCID: https://orcid.org/0000-0003-2159-5341)
- Marta Brunetti (ORCID: https://orcid.org/0000-0002-0150-2067)
- Maren Randi Tandsæther
- Kristin Andersen
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.3389/fonc.2024.1428984
- Primary Topic
- Acute Myeloid Leukemia Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00