Nasoseptal chondroprogenitors isolated through fibronectin-adherence confer no biological advantage for cartilage tissue engineering compared to nasoseptal chondrocytes
The fibronectin adhesion assay does not appear to reliably isolate a chondroprogenitor cell population from nasoseptal cartilage, and these cells confer no advantageous properties for cartilage tissue engineering. Refinement of cell isolation methods and chondroprogenitor markers is warranted for future nasoseptal cartilage tissue engineering efforts.
Authors
- Shareen H. Doak (ORCID: https://orcid.org/0000-0002-6753-1987)
- Nick S. Jones (ORCID: https://orcid.org/0000-0002-4083-972X)
- Thomas H. Jovic (ORCID: https://orcid.org/0000-0002-8325-0931)
- Iain S. Whitaker (ORCID: https://orcid.org/0000-0002-3922-2079)
- Catherine A. Thornton (ORCID: https://orcid.org/0000-0002-5153-573X)
- Emman J Thomson
Institutions
- Morriston Hospital (GB)
- Swansea University (GB)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.3389/fbioe.2024.1421111
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Scar Free Foundation
- VTCT Foundation
- Action Medical Research