A comprehensive analysis of genes associated with hypoxia and cuproptosis in pulmonary arterial hypertension using machine learning methods and immune infiltration analysis: AHR is a key gene in the cuproptosis process
<i>AHR</i>, <i>FAS</i>, and <i>FGF2</i> were identified as potential biomarkers for PAH, influencing cell proliferation and inflammatory responses, thereby offering new insights for PAH prevention and treatment.
Authors
- Ming Zhong (ORCID: https://orcid.org/0000-0002-6229-4943)
- Riken Chen (ORCID: https://orcid.org/0000-0001-6101-7891)
- Zuguang Chen
- Fengwei Xie (ORCID: https://orcid.org/0000-0002-2033-082X)
- Xishi Sun (ORCID: https://orcid.org/0000-0003-3841-4789)
- Zhihai Huang (ORCID: https://orcid.org/0000-0002-1110-3086)
- Junfen Cheng (ORCID: https://orcid.org/0000-0003-3130-7948)
- Kaili Fu
- Lingpin Pang
- Tao Huang (ORCID: https://orcid.org/0000-0002-9703-3604)
- Jie Sun (ORCID: https://orcid.org/0009-0006-5321-6827)
- Dingyu Guo (ORCID: https://orcid.org/0009-0000-7525-6615)
- Lingyue Song
- Chun-Yi Huang
- Xian Qian
Institutions
- Guangdong Medical College (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Central People's Hospital of Zhanjiang (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2024-09-26
- DOI
- https://doi.org/10.3389/fmed.2024.1435068
- Citations
- 4
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.68