Disparities in the Representation of Sex, Race and Ethnicity in Tension-Type Headache Clinical Trials
While tension-type headache (TTH) is the most common primary headache disorder, its effect according to sex, race and ethnicity remains unclear. We investigated disparities in sex, racial and ethnic representation in TTH clinical trials with comparison to global disease burdens. In this cross-sectional analysis, TTH clinical trials had female overrepresentation and racial and ethnic minority underrepresentation, which may affect understanding of the impact of TTH on different populations and personalized treatment development. Trial enrollment that is diverse and reflective of global disease burdens is crucial for improving study generalizability, understanding of diverse clinical presentations, and ensuring healthcare equity.
Authors
- Brendan Tao (ORCID: https://orcid.org/0000-0001-7069-3162)
- Chia‐Chen Tsai (ORCID: https://orcid.org/0000-0001-6907-1104)
- Sina Marzoughi (ORCID: https://orcid.org/0000-0003-4802-2391)
- Faisal Khosa (ORCID: https://orcid.org/0000-0001-5681-7683)
- Ana Marissa Lagman‐Bartolome (ORCID: https://orcid.org/0000-0002-4859-6216)
- Carmen Kalo
- Jaden Lo
- Arya Ebadi
Institutions
- Western University (CA)
- University of British Columbia (CA)
- King's College London (GB)
- University of Toronto (CA)
- London Health Sciences Centre (CA)
- Hospital for Sick Children (CA)
- Vancouver General Hospital (CA)
- SickKids Foundation (CA)
- Children's Hospital of Western Ontario (CA)
- McMaster University (CA)
Publication Details
- Journal
- Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1017/cjn.2024.300
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00