Functional metagenomics highlights varied infection states with dynamics of pathogens and antibiotic resistance in lower respiratory tract infections
The prevalence of common pathogens like <i>A. baumannii</i> and <i>K. pneumoniae</i> along with the non-respiratory pathogens identified by RPIP-Explify and CZID seq provided an understanding to evaluate the LRTI. mNGS is crucial for precise pathogen and antibiotic resistance detection, vital for combating antibiotic resistance.
Authors
- Pallawi Kumari
- Aanchal Yadav
- Rajesh Pandey (ORCID: https://orcid.org/0000-0002-4404-8327)
- Uzma Shamim (ORCID: https://orcid.org/0000-0001-8757-1209)
- Ranjeet Maurya (ORCID: https://orcid.org/0000-0002-0306-8970)
- Kriti Khare (ORCID: https://orcid.org/0000-0003-1108-8733)
- Bansidhar Tarai (ORCID: https://orcid.org/0000-0001-9742-9855)
- Priti Devi
- Kanika Kanika
Institutions
- Indraprastha Institute of Information Technology Delhi (IN)
- Institute of Genomics and Integrative Biology (IN)
- Max Super Speciality Hospital (IN)
- Max Healthcare (IN)
- Ashoka University (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38380
- Citations
- 4
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Bill and Melinda Gates Foundation
- Rockefeller Foundation
- Council of Scientific and Industrial Research, India