The revolution in high-throughput proteomics and AI

The recent capability to measure thousands of plasma proteins from a tiny blood sample has provided a new dimension of expansive data that can advance our understanding of human health. For example, the company SomaLogic has developed the means to measure more than 10,000 proteins and Thermo Fisher's Olink assays over 5400 proteins from as little as 2 μl. When these rich data are integrated with other layers of information from large patient cohorts, such as the UK Biobank's genetic, health, and lifestyle information from half a million participants, we get new insights about the underpinnings of disease, the aging process, and the potential ability to forecast an individual's health trajectory.

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Publication Details

Journal
Science
Published
2024-09-26
DOI
https://doi.org/10.1126/science.ads5749
Citations
24
Primary Topic
Health, Environment, Cognitive Aging
Type
article
Field-Weighted Citation Impact
7.55
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article

The revolution in high-throughput proteomics and AI

Eric J. Topol
24 citations
Science
Health, Environment, Cognitive Aging
7.55
article

The revolution in high-throughput proteomics and AI

Eric J. Topol
article en
24 citations

Abstract

The recent capability to measure thousands of plasma proteins from a tiny blood sample has provided a new dimension of expansive data that can advance our understanding of human health. For example, the company SomaLogic has developed the means to measure more than 10,000 proteins and Thermo Fisher's Olink assays over 5400 proteins from as little as 2 μl. When these rich data are integrated with other layers of information from large patient cohorts, such as the UK Biobank's genetic, health, and lifestyle information from half a million participants, we get new insights about the underpinnings of disease, the aging process, and the potential ability to forecast an individual's health trajectory.

ScienceVol. 385(6716)
Scripps Institution of Oceanography (US), Scripps (United States) (US)
Openalex Percentile: Top 2%
Health, Environment, Cognitive Aging
7.55
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