Development of Hot Melt Extruded Co-Formulated Artesunate and Amodiaquine- Soluplus<sup>®</sup> Solid Dispersion System in Fixed-Dose Form: Amorphous State Characterization and Pharmacokinetic Evaluation

Therefore, the developed melt extruded co-amorphous formulation has enhanced bioavailability and has more effectiveness than the marketed product Coarsucam<sup>®</sup>. .

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Publication Details

Journal
Current Drug Metabolism
Published
2024-09-26
DOI
https://doi.org/10.2174/0113892002330772240912055518
Citations
3
Primary Topic
Drug Solubulity and Delivery Systems
Type
article
Field-Weighted Citation Impact
0.62
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article

Development of Hot Melt Extruded Co-Formulated Artesunate and Amodiaquine- Soluplus® Solid Dispersion System in Fixed-Dose Form: Amorphous State Characterization and Pharmacokinetic Evaluation

Ritesh Fule, Purnima D. Amin, Musarrat Husain Warsi, Mohammed Kaleem et al.
3 citations
Current Drug Metabolism
Drug Solubulity and Delivery Systems
0.62
article

Development of Hot Melt Extruded Co-Formulated Artesunate and Amodiaquine- Soluplus® Solid Dispersion System in Fixed-Dose Form: Amorphous State Characterization and Pharmacokinetic Evaluation

Ritesh Fule, Purnima D. Amin, Musarrat Husain Warsi, Mohammed Kaleem, Md Ali Mujtaba, Meshal Meteab Majed Almoutairi, Gamal Osman Elhassan
article en
3 citations

Abstract

Therefore, the developed melt extruded co-amorphous formulation has enhanced bioavailability and has more effectiveness than the marketed product Coarsucam<sup>®</sup>. .

Current Drug MetabolismVol. 25(7)
Northern Border University (SA), Qassim University (SA), Institute of Chemical Technology (IN), Taif University (SA), Bombay College of Pharmacy (IN), Northern Area Armed Forces Hospital (SA)
Openalex Percentile: Top 36%
Drug Solubulity and Delivery Systems
0.62
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