Comparative Analysis of Traditional and Pharmacometric-Based Pharmacoeconomic Modeling in the Cost-Utility Evaluation of Sunitinib Therapy

Model structure significantly influences CUA predictions. The pharmacometric-based model framework more closely represented real-world toxicity trends and drug exposure changes. The relevance of these findings depends on the specific question a CUA seeks to address.

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Publication Details

Journal
PharmacoEconomics
Published
2024-09-26
DOI
https://doi.org/10.1007/s40273-024-01438-z
Citations
1
Primary Topic
Gastrointestinal Tumor Research and Treatment
Type
article
Field-Weighted Citation Impact
0.46

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article

Comparative Analysis of Traditional and Pharmacometric-Based Pharmacoeconomic Modeling in the Cost-Utility Evaluation of Sunitinib Therapy

Maddalena Centanni, Mats O. Karlsson, Lena E. Friberg, Janine Nijhuis
1 citations
PharmacoEconomics
Gastrointestinal Tumor Research and Treatment
0.46
article

Comparative Analysis of Traditional and Pharmacometric-Based Pharmacoeconomic Modeling in the Cost-Utility Evaluation of Sunitinib Therapy

Maddalena Centanni, Mats O. Karlsson, Lena E. Friberg, Janine Nijhuis
article en
1 citations

Abstract

Model structure significantly influences CUA predictions. The pharmacometric-based model framework more closely represented real-world toxicity trends and drug exposure changes. The relevance of these findings depends on the specific question a CUA seeks to address.

PharmacoEconomicsVol. 43(1)
Uppsala University (SE)
Cancerfonden, Vetenskapsrådet, Uppsala Universitet
Openalex Percentile: Top 33%
Gastrointestinal Tumor Research and Treatment
0.46
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