A Rare Case of Necrotizing Pneumonia and Pleural Empyema Secondary to Transdiaphragmatic Extension and Perforation of a Pyogenic Liver Abscess

This article presents a rare case of an elderly patient with diabetes and hypertension who developed a primary pyogenic liver abscess (PLA) that subsequently disseminated to the lungs by contiguity, resulting in diaphragmatic perforation complicated by necrotizing pneumonia, hepatobronchial fistula, and pleural empyema. In this case, percutaneous drainage of the PLA was unsuccessful, necessitating surgical intervention, which confirmed the diaphragmatic perforation. <i>Klebsiella pneumoniae</i> was isolated from the liver abscess samples sent for microbiological analysis, while blood cultures were negative. Despite extensive local infection and systemic dissemination consistent with invasive liver abscess syndrome, as well as progression to septic shock requiring intensive care unit admission, the patient achieved a gradual yet full recovery and ultimately returned to an active daily life. This was only possible due to the effective control of the infectious focus, combined with appropriate antibiotic therapy and supportive measures.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2024-09-26
DOI
https://doi.org/10.7759/cureus.70273
Primary Topic
Amoebic Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A Rare Case of Necrotizing Pneumonia and Pleural Empyema Secondary to Transdiaphragmatic Extension and Perforation of a Pyogenic Liver Abscess

Jorge M. Mendes, Fernando Guilhon Henriques, Gonçalo Paiva Dias, Ricardo Marinho et al.
1 links
Cureus
Amoebic Infections and Treatments
article

A Rare Case of Necrotizing Pneumonia and Pleural Empyema Secondary to Transdiaphragmatic Extension and Perforation of a Pyogenic Liver Abscess

Jorge M. Mendes, Fernando Guilhon Henriques, Gonçalo Paiva Dias, Ricardo Marinho, Miguel G Santos
article en

Abstract

This article presents a rare case of an elderly patient with diabetes and hypertension who developed a primary pyogenic liver abscess (PLA) that subsequently disseminated to the lungs by contiguity, resulting in diaphragmatic perforation complicated by necrotizing pneumonia, hepatobronchial fistula, and pleural empyema. In this case, percutaneous drainage of the PLA was unsuccessful, necessitating surgical intervention, which confirmed the diaphragmatic perforation. <i>Klebsiella pneumoniae</i> was isolated from the liver abscess samples sent for microbiological analysis, while blood cultures were negative. Despite extensive local infection and systemic dissemination consistent with invasive liver abscess syndrome, as well as progression to septic shock requiring intensive care unit admission, the patient achieved a gradual yet full recovery and ultimately returned to an active daily life. This was only possible due to the effective control of the infectious focus, combined with appropriate antibiotic therapy and supportive measures.

CureusVol. 16(9)
Instituto Politécnico de Leiria (PT)
Zero hunger
Openalex Percentile: Top 79%
Amoebic Infections and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.