Whole-Body Vibration Affects Hippocampal Choline Acetyltransferase and Synaptophysin Expression and Improves Spatial Memory in Young Adult Mice
Our results indicate that WBV stimulates the septo-hippocampal cholinergic system in a gradual and dynamic way that may contribute to improved spatial-memory performance. This finding suggests that WBV, by upregulation of the septo-hippocampal cholinergic system, may be considered a valuable therapeutic strategy to enhance brain functions in aging, neurodegenerative, and other brain diseases.
Authors
- Eddy A. van der Zee (ORCID: https://orcid.org/0000-0002-6471-7938)
- Marieke J. G. van Heuvelen (ORCID: https://orcid.org/0000-0002-5402-0790)
- Wouter Huiting (ORCID: https://orcid.org/0000-0002-0371-512X)
- Tamás Oroszi (ORCID: https://orcid.org/0000-0003-2327-9959)
- Csaba Nyakas (ORCID: https://orcid.org/0000-0003-3756-0186)
- Jan N. Keijser
Institutions
- Semmelweis University (HU)
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Hungarian School Sport Federation (HU)
Publication Details
- Journal
- Journal of Integrative Neuroscience
- Published
- 2024-09-23
- DOI
- https://doi.org/10.31083/j.jin2309173
- Citations
- 1
- Primary Topic
- Effects of Vibration on Health
- Type
- article
- Field-Weighted Citation Impact
- 0.48