A high-throughput liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of <i>p</i> -cresol sulfate, <i>p</i> -cresol glucuronide, indoxyl sulfate, and indoxyl glucuronide in HepaRG culture medium and the demonstrat
This novel assay is capable of quantifying these metabolites in HepaRG cells. Our novel findings suggest that mefenamic acid can be potentially utilized therapeutically to attenuate <i>p</i>CS-associated toxicities.
Authors
- Tony K. L. Kiang (ORCID: https://orcid.org/0000-0003-4548-9746)
- Ala’a R. Al-Dajani
Institutions
- University of Alberta (CA)
Publication Details
- Journal
- Expert Opinion on Drug Metabolism & Toxicology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1080/17425255.2024.2409257
- Citations
- 1
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.42