THERAPEUTIC EFFECTIVENESS OF PHYTOEXTRACTS AND PROBIOTICS FOR DYSPEPSIC DISORDERS IN CALVES

The aim of the study is to comparatively evaluate the therapeutic efficacy of a phytoextract + probiotic complex in treating dyspeptic disorders in calves. For the experiment, three groups of newborn calves with signs of dyspeptic disorders were formed, 10 animals in each (n = 30). The first experimental group of calves was given a 4 : 1 mixture of St. John's wort extract Hypericum perforatum+probiotic at a dose of 5 ml/kg of live weight twice a day with an interval of 12 hours; the second experimental group was given bird cherry fruit extract Cerasis fructus + probiotic at a dose of 5 ml/kg of live weight twice a day with an interval of 12 hours; the control group of animals was given the probiotic Bacillus amyloliquefaciens strain VKPM B-10642 at least 1∙106 CFU of live bacterial spores at a dose of 5 ml/kg once. The obtained data indicate that both of the above-mentioned complexes have a pronounced therapeutic effect: in the first and second experimental groups of animals 90 and 100 %, respectively, in the control group – 70 %. When comparing the blood serum indicators for Na and K, normalization of water-salt metabolism in the body of newborn calves was noted. Thus, in the control group, a decrease in these indicators by 29.2 and 17.1 % was observed compared to the average value of the first and second experimental groups. Using plant extracts of bird cherry and St. John's wort in combination with a probiotic for dyspeptic disorders of newborn calves, livestock farms will be able to reduce economic losses from lost weight gain (by 18.8 %), calf mortality (by 30 %), eliminating the negative impact of chemical drugs on the body of animals, humans and the environment.