Analysis of Follow-up Real-Time RT-PCR Results from SARS-CoV-2-Positive Patients

pitalized patients were not clear, leading to many patients remaining hospitalized until their real-time reverse transcription-polymerase chain reaction (rRT-PCR; hereinafter referred to as PCR) tests returned negative results.The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) PCR test is crucial for diagnosing COVID-19 [1, 2], monitoring the disease progression [3, 4], and determining whether hospitalized patients can be discharged [5, 6].However, interpreting the PCR result can be more challenging during follow-up than at the time of diagnosis.During the initial diagnosis, a large amount of virus particles is present in the test specimen, making it easy to determine positive or negative results.However, during follow-up testing, especially at the time of discharge, the virus concentration is low, rendering interpretation of the results difficult.

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Publication Details

Journal
Laboratory Medicine Online
Published
2024-09-26
DOI
https://doi.org/10.47429/lmo.2024.14.4.369
Primary Topic
SARS-CoV-2 detection and testing
Type
article
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article

Analysis of Follow-up Real-Time RT-PCR Results from SARS-CoV-2-Positive Patients

Eun‐Hyung Yoo, Chang‐Ho Jeon
Laboratory Medicine Online
SARS-CoV-2 detection and testing
article

Analysis of Follow-up Real-Time RT-PCR Results from SARS-CoV-2-Positive Patients

Eun‐Hyung Yoo, Chang‐Ho Jeon
article en

Abstract

pitalized patients were not clear, leading to many patients remaining hospitalized until their real-time reverse transcription-polymerase chain reaction (rRT-PCR; hereinafter referred to as PCR) tests returned negative results.The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) PCR test is crucial for diagnosing COVID-19 [1, 2], monitoring the disease progression [3, 4], and determining whether hospitalized patients can be discharged [5, 6].However, interpreting the PCR result can be more challenging during follow-up than at the time of diagnosis.During the initial diagnosis, a large amount of virus particles is present in the test specimen, making it easy to determine positive or negative results.However, during follow-up testing, especially at the time of discharge, the virus concentration is low, rendering interpretation of the results difficult.

Laboratory Medicine OnlineVol. 14(4)
Daegu Catholic University (KR)
Openalex Percentile: Top 79%
SARS-CoV-2 detection and testing
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