CuI-Catalyzed Selenylation of Pyrrolo[2,1-<i>a</i>]isoquinolines and Other Electron-Rich Heteroarenes
We have established a mild CuI-catalyzed selenylation of pyrrolo[2,1-<i>a</i>]isoquinoline derivatives in the presence of <i>m</i>CPBA (<i>m</i>-chloroperoxybenzoic acid) at ambient temperature. Corresponding organoselenides have been prepared readily in 53-92% yields. This process can also be expanded to the modification of pyrroles, azaindole, and indoles, delivering the desired heterocyclic selenides in moderate to good yields.
Authors
- Hai‐Lei Cui (ORCID: https://orcid.org/0000-0002-8248-6627)
- Yun‐Meng Li
- Yu Xin (ORCID: https://orcid.org/0000-0002-6946-6410)
- Yang Liu (ORCID: https://orcid.org/0000-0001-6757-3522)
- Man Jiang (ORCID: https://orcid.org/0000-0002-3182-6863)
- Jing Zhou (ORCID: https://orcid.org/0000-0001-5074-2502)
- Jiayi Han
Institutions
- Chongqing University of Arts and Sciences (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1021/acs.joc.4c01462
- Citations
- 9
- Primary Topic
- Organoselenium and organotellurium chemistry
- Type
- article
- Field-Weighted Citation Impact
- 3.16
Funders
- National Natural Science Foundation of China
- Chongqing Municipal Education Commission