Effect of Jianpi Wenshen Granules on the Nutritional Control Status Score in Elderly Patients Undergoing Maintenance Hemodialysis

Objective: To explore the effect of Jianpi Wenshen Granules on the Controlling Nutritional Status (CONUT) score in elderly patients undergoing maintenance hemodialysis. Methods: Seventy elderly outpatients undergoing maintenance hemodialysis from January 2023 to January 2024 at the Blood Purification Centers of Taizhou Traditional Chinese Medicine Hospital and Taizhou Second People’s Hospital were selected as the study subjects. The patients were randomly divided into two groups: the study group and the control group, with 35 patients in each group. Both groups received maintenance hemodialysis, while the control group received only conventional Western medicine treatment, and the study group was additionally treated with Jianpi Wenshen Granules. The changes in biochemical and inflammatory markers before and after treatment were compared between the two groups. The nutritional status of the patients was assessed using the Controlling Nutritional Status (CONUT) score, and detailed statistics were gathered on anemia and albumin levels in both groups. Results: After treatment, the CONUT score in the study group significantly decreased compared to the control group, showing a significant correlation (P < 0.05). Albumin and hemoglobin levels significantly increased, with a notable difference (P < 0.05). There were no significant differences in alanine aminotransferase and aspartate aminotransferase levels between the two groups before and after treatment (P > 0.05). Conclusion: In elderly patients undergoing maintenance hemodialysis, Jianpi Wenshen Granules improve the CONUT score and enhance nutritional status, demonstrating potential for clinical application and promotion.