Serum TNF alpha concentration and arterial age of patients with acute cerebral infarction

Aims: To determine the serum TNF-α concentration and arterial age of patients with acute cerebral infarction; and explore the relationship between serum TNF-α concentration and arterial age with age, gender, smoking history, blood pressure, blood lipid profile, diabetes, ejection fraction, carotid atherosclerosis in patients with acute cerebral infarction. Methods: A cross-sectional descriptive study was conducted on patients with acute cerebral infarction at the Department of Intensive Care and Stroke - Hue Central Hospital from May 2023 to June 2024. Clinical and paraclinical results were used to analyze factors related to TNF-α. Results: The average TNF-α concentration was 23.81 ± 9.11 (pg/mL). Patients with arterial age (76.37 ± 8.05) were greater than actual age (68.63 ± 12.32) significantly (p < 0.001). There was a correlation between smoking, hypertension, diabetes, ejection fraction (EF), carotid atherosclerosis and arterial age with TNF-α. Conclusion: In patients with acute cerebral infarction, TNF-α concentration was increased. Arterial age was greater than the actual age of the patient.