Eosinophilic Granulomatous Interstitial Nephritis in Eosinophilic Granulomatous Polyangiitis
A 74-year-old woman with bronchial asthma and schizophrenia was admitted to our hospital with leg numbness and eosinophilia.Laboratory tests revealed the following: eosinophils, 11,840/L; creatinine (Cr), 0.78 mg/dL; urinary protein/Cr ratio, 0.77 g/gCr without hematuria; and urinary 2microglobulin, 83,900 g/L.Myeloperoxidase and proteinase 3 antineutrophil cytoplasmic antibody tests were negative.Computed tomography revealed ground-glass opacities in both lungs, and magnetic resonance imaging (T2-weighted imaging) revealed high-intensity lesions in the left ventricular anterior wall and septum.A renal biopsy revealed eosinophilic infiltrates (arrowheads, Picture 1) and non-
Authors
- Izaya Nakaya (ORCID: https://orcid.org/0000-0002-0792-6514)
- Tokio Katakura (ORCID: https://orcid.org/0009-0003-0507-9969)
- Machi Kiyohara
- Yuki Nakamura (ORCID: https://orcid.org/0000-0003-4931-2489)
Institutions
- Iwate Prefectural Central Hospital (JP)
Publication Details
- Journal
- Internal Medicine
- Published
- 2024-09-26
- DOI
- https://doi.org/10.2169/internalmedicine.4274-24
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00