The Dark Side of the Sunshine Vitamin: A Case of Acute Renal Failure and Hypercalcaemia From Vitamin D Overconsumption

Vitamin D toxicity is a rare but potentially serious condition that can lead to severe hypercalcaemia and subsequent complications, such as acute renal failure, nephrocalcinosis, congestive heart failure and coronary calcium deposition, resulting in myocardial injury. We present a case of a 76-year-old male patient who developed severe hypercalcaemia and acute kidney injury due to excessive long-term over-the-counter vitamin D supplementation. The patient was initially treated with aggressive intravenous fluids and furosemide. However, a failed effective response prompted the addition of pamidronate, resulting in the gradual improvement of hypercalcaemia and renal function. We have presented, in this case, a rare adverse effect of vitamin D toxicity and its multiorgan effect.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2024-09-26
DOI
https://doi.org/10.7759/cureus.70237
Citations
1
Primary Topic
Vitamin D Research Studies
Type
article
Field-Weighted Citation Impact
0.42
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

The Dark Side of the Sunshine Vitamin: A Case of Acute Renal Failure and Hypercalcaemia From Vitamin D Overconsumption

Sheharyar Khan, Muhammad U. Manzoor, Muhammad Tariq, Muhammad Nadeem Akhtar et al.
1 citations
Cureus
Vitamin D Research Studies
0.42
article

The Dark Side of the Sunshine Vitamin: A Case of Acute Renal Failure and Hypercalcaemia From Vitamin D Overconsumption

Sheharyar Khan, Muhammad U. Manzoor, Muhammad Tariq, Muhammad Nadeem Akhtar, Muhammad Tanseer Sibtain Raza
article en
1 citations

Abstract

Vitamin D toxicity is a rare but potentially serious condition that can lead to severe hypercalcaemia and subsequent complications, such as acute renal failure, nephrocalcinosis, congestive heart failure and coronary calcium deposition, resulting in myocardial injury. We present a case of a 76-year-old male patient who developed severe hypercalcaemia and acute kidney injury due to excessive long-term over-the-counter vitamin D supplementation. The patient was initially treated with aggressive intravenous fluids and furosemide. However, a failed effective response prompted the addition of pamidronate, resulting in the gradual improvement of hypercalcaemia and renal function. We have presented, in this case, a rare adverse effect of vitamin D toxicity and its multiorgan effect.

CureusVol. 16(9)
Nottingham University Hospitals NHS Trust (GB), Grantham and District Hospital (GB), University Hospital Southampton NHS Foundation Trust (GB), United Lincolnshire Hospitals NHS Trust (GB)
Zero hunger
Openalex Percentile: Top 35%
Vitamin D Research Studies
0.42
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.