Study of bone mineral disorders in hemodialysis patients at Hue Central Hospital

Aims: Early detection and correction of calcium-phosphate imbalances to improve symptoms of hyperuremia, slow the progression of chronic kidney disease and reduce the risk of death from cardiovascular complications and renal osteodystrophy dues to secondary hyperparathyroidism.Methods: Cross-sectional study on 101 patients with end-stage chronic kidney disease on hemodialysis at the Hemodialysis Department in Hue Central Hospital.Results: The rate of bone mineral factor disorders was arranged in the order of phosphorus (86,1%), calcium x P (60,4%), PTH (49,5%) and calcium (19,8%). There were 12 patients (11,9%) with osteoporosis and 38 patients (37,6%) with osteopenia. There were 60 patients (59,4%) with abdominal aortic calcification. There were 11 patients (10,89%) acquire heart valve calcification. Age and BMI predicted the risk of decreased bone density at all 3 locations: lumbar spine, total femur and femoral neck with p < 0,0001. Age and time of dialysis predicted the risk of abdominal aortic calcification, in which age had the highest predictive value (OR = 1,07, p < 0,0001).Conclusion: The rate of patients with bone mineral disorders in the study group is still high. More attention should be paid to the detection and correction of bone mineral disorders according to KDIGO 2017 recommendations in patients on hemodialysis.