The molecular regulated mechanism of METTL3 and FTO in lipid metabolism of Hu sheep
METTL3 significantly inhibited the expression of lipid deposition-related genes, whereas FTO overexpression promoted lipid deposition. Our study provides a theoretical basis and reference for accurately regulating animal lipid deposition by mastering METTL3 and FTO genes to promote high-quality animal husbandry.
Authors
- Zengkui Lu (ORCID: https://orcid.org/0000-0002-5993-1083)
- Chao Yuan (ORCID: https://orcid.org/0000-0003-1315-0166)
- Tingting Guo (ORCID: https://orcid.org/0000-0003-4472-5444)
- Bowen Chen (ORCID: https://orcid.org/0000-0002-9402-6679)
- Jianbin Liu (ORCID: https://orcid.org/0000-0001-6550-9236)
- Bohui Yang (ORCID: https://orcid.org/0000-0001-7516-8914)
Institutions
- Lanzhou Institute of Husbandry and Pharmaceutical Sciences (CN)
Publication Details
- Journal
- Genomics
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1016/j.ygeno.2024.110945
- Citations
- 4
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.14