A novel effect of sulforaphane on promoting mouse granulosa cells proliferation via the NRF2–TKT pathway
Collectively, our findings delineate a novel pathway by which SFN, through the NRF2-TKT axis, enhances the nucleotide pool and thereby supports the proliferation of mouse GCs, presenting novel avenues for exploration in reproductive biology and agricultural sciences.
Authors
- Xinyi Zhou (ORCID: https://orcid.org/0000-0002-3471-2984)
- Cai‐Xia Yang (ORCID: https://orcid.org/0000-0003-3275-8281)
- Dingding Zhang (ORCID: https://orcid.org/0000-0002-5234-752X)
- Honglin Liu (ORCID: https://orcid.org/0000-0002-1254-3163)
- Jingli Tao (ORCID: https://orcid.org/0000-0001-5761-6963)
- Kang Zou (ORCID: https://orcid.org/0000-0002-1253-1816)
- Ming Shen (ORCID: https://orcid.org/0000-0003-1219-225X)
- Jiaqi Zhou (ORCID: https://orcid.org/0000-0002-9285-8914)
- Xuan Zhang (ORCID: https://orcid.org/0009-0001-5867-8549)
- Aoyun Fan
Institutions
- Nanjing Agricultural University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1016/j.jare.2024.09.020
- Citations
- 5
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Jiangsu Agricultural Science and Technology Innovation Fund
- National Natural Science Foundation of China
- Government of Jiangsu Province
- National Science and Technology Major Project
- Fundamental Research Funds for the Central Universities