Evaluating the efficacy of whole genome sequencing in predicting susceptibility profiles for first-line antituberculosis drugs
Integrating WGS into tuberculosis management offers significant potential to replace phenotypic drug susceptibility testing, especially for problematic drugs like pyrazinamide and ethambutol, potentially improving treatment outcomes.
Authors
- Chiara Vismara (ORCID: https://orcid.org/0009-0005-9538-088X)
- Giulia Russo (ORCID: https://orcid.org/0000-0001-6616-7856)
- Alberto Matteelli (ORCID: https://orcid.org/0000-0001-5109-9248)
- Stefania Torri
- Arash Ghodousi (ORCID: https://orcid.org/0000-0001-9334-1573)
- Luigi Ruffo Codecasa (ORCID: https://orcid.org/0000-0001-6825-2050)
- Daniela María Cirillo (ORCID: https://orcid.org/0000-0001-6415-1535)
- Maryam Omrani (ORCID: https://orcid.org/0000-0002-0056-109X)
- Hedyeh Teymouri
Institutions
- Vita-Salute San Raffaele University (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- University of Brescia (IT)
Publication Details
- Journal
- Clinical Microbiology and Infection
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1016/j.cmi.2024.09.024
- Citations
- 5
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- Ministero della Salute