Combination of serological and cytokine release assays for improved diagnosis of childhood tuberculosis in Zambia (PROMISE-TB)
This study suggests that supplementing the QuantiFERON assay with a combination of serological and T-cell markers could enhance childhood TB screening regardless of HIV status and age. Further validation among the target population is necessary to confirm the performance of this scoring system.
Authors
- Nicolas Nagot (ORCID: https://orcid.org/0000-0002-3493-2821)
- Marianne Périés (ORCID: https://orcid.org/0000-0002-6791-4419)
- Roselyne Vallo (ORCID: https://orcid.org/0000-0002-2447-6754)
- Jean‐Pierre Molès (ORCID: https://orcid.org/0000-0002-6863-6350)
- Duncan Chanda (ORCID: https://orcid.org/0000-0001-5477-9054)
- Pierre‐Alain Rubbo
- Amandine Pisoni (ORCID: https://orcid.org/0000-0001-5426-3998)
- Chipepo Kankasa
- Philippe Van de Perre (ORCID: https://orcid.org/0000-0002-3912-0427)
- Sabrina Eymard‐Duvernay
- Laurent Kremer (ORCID: https://orcid.org/0000-0002-6604-4458)
- Matthias Richard (ORCID: https://orcid.org/0000-0002-7999-7653)
- Édouard Tuaillon (ORCID: https://orcid.org/0000-0001-5866-9530)
- Morgana D’Ottavi (ORCID: https://orcid.org/0000-0002-6398-6300)
- Mwiya Mwyia
- Maria M.W. Tonga
- Karine Bolloré (ORCID: https://orcid.org/0000-0002-2142-0755)
Institutions
- Inserm (FR)
- Université de Montpellier (FR)
- University Teaching Hospital (ZM)
- Centre Hospitalier Universitaire de Montpellier (FR)
- Établissement Français du Sang (FR)
- Institut de Recherche en Infectiologie de Montpellier (FR)
- Pathogenesis and Control of Chronic and Emerging Infections (FR)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1016/j.ijid.2024.107248
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Styrelsen för Internationellt Utvecklingssamarbete
- Agence Nationale de Recherches sur le Sida et les Hépatites Virales
- European and Developing Countries Clinical Trials Partnership