Investigating the uncertain causal link between gut microbiota and glaucoma: A genetic correlation and Mendelian randomisation study
While our study provides some evidence of associations between specific GM taxa and glaucoma, the results underscore the complexity of these relationships and the need for further research to clarify the potential causal links. The findings highlight the importance of interpreting the gut-eye axis with caution and suggest that while GM may play a role in glaucoma, it is unlikely to be a predominant causal factor.
Authors
- Yuxian He (ORCID: https://orcid.org/0000-0003-2048-6696)
- Shicheng Guo (ORCID: https://orcid.org/0000-0002-7047-9972)
- Mingkai Lin (ORCID: https://orcid.org/0000-0003-2610-6658)
- Xin Ma (ORCID: https://orcid.org/0000-0001-6250-7737)
- Wei Wang (ORCID: https://orcid.org/0000-0002-5273-3332)
- Xu Zhang (ORCID: https://orcid.org/0000-0002-2880-7012)
- Xinbo Gao (ORCID: https://orcid.org/0000-0001-9138-3366)
- Chao Tang (ORCID: https://orcid.org/0000-0002-2091-3355)
- Jiayong Li (ORCID: https://orcid.org/0000-0002-6154-762X)
- Kaichen Zhuo
Institutions
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Chongqing Maternal and Child Health Hospital (CN)
- Children's Hospital of Zhejiang University (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Clinical and Experimental Ophthalmology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1111/ceo.14440
- Citations
- 8
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 4.31
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province