The prognostic utility of the neutrophil to lymphocyte ratio in paediatric brain tumours: a retrospective case control study

A high NLR was associated with an increased odds of having a malignant PBT but a reliable cut-off point was not identified and the underlying mechanisms for this remain unknown. The NLR is a poor diagnostic biomarker due to its poor overall sensitivity and specificity. More research is required to further study the role of immunity in PBTs.

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Journal
British Journal of Neurosurgery
Published
2024-09-26
DOI
https://doi.org/10.1080/02688697.2024.2406804
Primary Topic
Inflammatory Biomarkers in Disease Prognosis
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article
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article

The prognostic utility of the neutrophil to lymphocyte ratio in paediatric brain tumours: a retrospective case control study

Ming-Sheng Lim, Darach Crimmins
British Journal of Neurosurgery
Inflammatory Biomarkers in Disease Prognosis
article

The prognostic utility of the neutrophil to lymphocyte ratio in paediatric brain tumours: a retrospective case control study

Ming-Sheng Lim, Darach Crimmins
article en

Abstract

A high NLR was associated with an increased odds of having a malignant PBT but a reliable cut-off point was not identified and the underlying mechanisms for this remain unknown. The NLR is a poor diagnostic biomarker due to its poor overall sensitivity and specificity. More research is required to further study the role of immunity in PBTs.

British Journal of NeurosurgeryVol. 40(1)
Beaumont Hospital (IE), Botsford Hospital (US), Temple Street Children's University Hospital (IE), Beaumont Hospital, Dearborn (US)
Good health and well-being
Openalex Percentile: Top 70%
Inflammatory Biomarkers in Disease Prognosis
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