Molecular genotyping reveals multiple carbapenemase genes and unique blaOXA-51-like (oxaAb) alleles among clinically isolated Acinetobacter baumannii from a Philippine tertiary hospital

In summary, this study highlighted the importance of molecular genotyping in the characterization of A. baumannii by revealing the carbapenemase profiles of the pathogen (which may not be captured accurately in phenotypic tests), in identifying potent carriers of transferrable carbapenemase genes (which may not be expressed straightforwardly in antimicrobial susceptibility testing), and in monitoring unique pathogen epidemiology in the local clinical setting.

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Publication Details

Journal
Tropical Medicine and Health
Published
2024-09-26
DOI
https://doi.org/10.1186/s41182-024-00629-w
Citations
5
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
0.85

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article

Molecular genotyping reveals multiple carbapenemase genes and unique blaOXA-51-like (oxaAb) alleles among clinically isolated Acinetobacter baumannii from a Philippine tertiary hospital

Raul V. Destura, Windell L. Rivera, Mark B. Carascal
5 citations
Tropical Medicine and Health
Antibiotic Resistance in Bacteria
0.85
article

Molecular genotyping reveals multiple carbapenemase genes and unique blaOXA-51-like (oxaAb) alleles among clinically isolated Acinetobacter baumannii from a Philippine tertiary hospital

Raul V. Destura, Windell L. Rivera, Mark B. Carascal
article en
5 citations

Abstract

In summary, this study highlighted the importance of molecular genotyping in the characterization of A. baumannii by revealing the carbapenemase profiles of the pathogen (which may not be captured accurately in phenotypic tests), in identifying potent carriers of transferrable carbapenemase genes (which may not be expressed straightforwardly in antimicrobial susceptibility testing), and in monitoring unique pathogen epidemiology in the local clinical setting.

Tropical Medicine and HealthVol. 52(1)
University of the Philippines Manila (PH), University of the Philippines Diliman (PH), University of Asia and the Pacific (PH)
University of the Philippines
Openalex Percentile: Top 30%
Antibiotic Resistance in Bacteria
0.85
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