NON-DESTRUCTIVE ANALYSIS OF TETRACYCLINE DRUGS BY DIGITAL COLORMETRIC METHOD USING A SMARTPHONE AND SOFTWARE PHOTOMETRIXPRO®

A non-destructive analysis of tetracyclines in drugs by their own fluorescence using a smartphone and a device printed on a 3D printer is proposed. The possibility of using chemometric methods, which reduce the analysis time and visualize the obtained data, is shown. The dataset was processed by principal component analysis (PCA), hierarchical cluster analysis (HCA), partial least squares regression (PLS), and least squares using PhotoMetrix PRO® software. The use of chemometric methods of analysis to determine the concentration of the active substance and identify the manufacturer of medicinal products is considered.