Sex-dependent effects of acute stress and alcohol exposure during adolescence on mRNA expression of brain signaling systems involved in reward and stress responses in young adult rats
This study demonstrates that adolescent acute stress and alcohol exposure induce lasting, sex-specific alterations in systems involved in reward and stress responses. These findings emphasize the importance of considering sex differences in the prevention and management of HPA dysfunction and psychiatric disorders.
Authors
- María Flores-López (ORCID: https://orcid.org/0000-0003-3489-1465)
- Laura Sánchez‐Marín (ORCID: https://orcid.org/0000-0002-1160-4964)
- Antonia Serrano (ORCID: https://orcid.org/0000-0002-8017-9754)
- Fernando Rodrı́guez de Fonseca (ORCID: https://orcid.org/0000-0002-4516-5795)
- Dina Medina‐Vera (ORCID: https://orcid.org/0000-0002-0342-1287)
- Francisco Javier Pavón (ORCID: https://orcid.org/0000-0002-5256-8904)
- Carlotta Gobbi
Institutions
- Instituto de Salud Carlos III (ES)
- Centro de Investigación en Red en Enfermedades Cardiovasculares (ES)
- Hospital Regional Universitario de Málaga (ES)
- Andalusian Centre for Nanomedicine and Biotechnology (ES)
- Hospital Clínico Universitario Virgen de la Victoria (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1186/s13293-024-00649-5
- Citations
- 5
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 1.46
Funders
- European Commission
- Junta de Andalucía
- Plan Nacional sobre Drogas
- Instituto de Salud Carlos III
- European Regional Development Fund