Histone variant H2AZ1 drives lung cancer progression through the RELA-HIF1A-EGFR signaling pathway
H2AZ1 plays an oncogenic role via several cancer-related pathways, including the RELA-HIF1A-EGFR axis in lung cancer. Intervention targeting H2AZ1 and its related signaling genes may have translational potential for precision therapy.
Authors
- Guoan Chen (ORCID: https://orcid.org/0000-0001-5608-6761)
- Xiaofei Zeng (ORCID: https://orcid.org/0000-0002-7408-5735)
- Zhiqing Zhou (ORCID: https://orcid.org/0000-0002-9623-3997)
- Xing Wu (ORCID: https://orcid.org/0000-0003-3887-9172)
- Huijie Zhao
- Yu Li (ORCID: https://orcid.org/0000-0003-3056-2680)
- Xiuling Li (ORCID: https://orcid.org/0000-0003-1175-2622)
- Yue Liu (ORCID: https://orcid.org/0000-0003-1759-9147)
- Yinghan Wang (ORCID: https://orcid.org/0000-0001-9963-9522)
- Yuhui Du (ORCID: https://orcid.org/0000-0002-2036-5408)
Institutions
- Sun Yat-sen University (CN)
- Southern University of Science and Technology (CN)
- Agricultural Genomics Institute at Shenzhen (CN)
- Sun Yat-sen Memorial Hospital (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1186/s12964-024-01823-3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China