Non-thermal atmospheric pressure plasma induces selective cancer cell apoptosis by modulating redox homeostasis
Our study demonstrates that NTAPP induces selective cell death in fibrosarcoma cells through the downregulation of the NRF2-induced ROS scavenger system and inhibition of autophagy. These findings suggest NTAPP's potential as a cancer therapy that minimizes damage to normal cells while effectively targeting cancer cells.
Authors
- Yoon Hee Yang (ORCID: https://orcid.org/0009-0001-1546-6167)
- Ju Hyun Yun
- Chang Hak Han
- Chul‐Ho Kim (ORCID: https://orcid.org/0000-0002-2161-4488)
- Sung Un Kang
Institutions
- Ewha Womans University (KR)
- Ajou University (KR)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1186/s12964-024-01810-8
- Citations
- 14
- Primary Topic
- Plasma Applications and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 5.66
Funders
- National Research Foundation
- Ministry of Environment
- Ministry of Science, ICT and Future Planning
- Ministry of Health and Welfare
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Education, India