A SRC-slug-TGFβ2 signaling axis drives poor outcomes in triple-negative breast cancers
Targeting the SRC-Slug-TGFβ2 axis may therefore lead to better treatment options and improve patient outcomes in this highly aggressive subpopulation of TNBCs.
Authors
- Shannon Beattie
- Paul B. Mullan (ORCID: https://orcid.org/0000-0003-1479-7084)
- Niamh E. Buckley (ORCID: https://orcid.org/0000-0001-9326-8513)
- Alexander J. McIntyre (ORCID: https://orcid.org/0000-0002-8411-2581)
- Scott Monteith
- Cristina Branco (ORCID: https://orcid.org/0000-0001-6953-4922)
- Francisco Liberal (ORCID: https://orcid.org/0000-0002-7917-8578)
- Charlotte Zoe Angel (ORCID: https://orcid.org/0000-0002-1951-9705)
- Shudong Zhang (ORCID: https://orcid.org/0000-0002-7721-0167)
- Paula Haddock
- Ezanee Azlina Mohamad Hanif (ORCID: https://orcid.org/0000-0002-7386-7727)
- Madina Sharifova
- Emma Parker
- S. R. Haynes
- M Ryan
Institutions
- Queen's University Belfast (GB)
- University of Ulster (GB)
- Altnagelvin Area Hospital (GB)
- The Northern Ireland Cancer Centre (GB)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1186/s12964-024-01793-6
- Citations
- 2
- Primary Topic
- TGF-β signaling in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Department of Health, Northern Ireland
- Public Health Agency
- Breast Cancer Ireland