Unmasking SARS-CoV-2’s coagulation conspiracy: the role of Spike
The recent study by Ryu et al. demonstrates that the SARS-CoV-2 Spike protein binds fibrin(ogen), impacting coagulation and immune responses in mice. In this spotlight article we focus on the described effects on natural killer (NK) cell responses as well as the suggested translation into potential new therapeutic targets against COVID-19.
Authors
- Helena Radbruch (ORCID: https://orcid.org/0000-0001-6941-3397)
- Tom Aschman (ORCID: https://orcid.org/0000-0002-2101-6146)
Institutions
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Trends in Immunology
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1016/j.it.2024.09.007
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00