Comprehensive Study on Central Precocious Puberty: Molecular and Clinical Analyses in 90 Patients
(Epi)genetic causes were identified in 12.2% of patients with CPP at our center. For patients with CPP born SGA or together with family histories of paternal early puberty, (epi)genetic testing for TS14 and MKRN3 genetic defects should be considered.
Authors
- Masayo Kagami (ORCID: https://orcid.org/0000-0003-3020-455X)
- Reiko Horikawa (ORCID: https://orcid.org/0000-0003-3429-3246)
- Tsutomu Ogata (ORCID: https://orcid.org/0000-0001-7178-9991)
- Hiromune Narusawa
- Mitsukazu Mamada
- Yasuhiro Naiki (ORCID: https://orcid.org/0000-0002-6338-895X)
- Sumito Dateki (ORCID: https://orcid.org/0000-0001-9588-4803)
- Shun Soneda
- Tomohiro Saito (ORCID: https://orcid.org/0000-0002-9916-4640)
- Satoshi Narumi (ORCID: https://orcid.org/0000-0002-0940-4517)
- Shintaro Terashita (ORCID: https://orcid.org/0000-0003-1559-0229)
- Hideaki Yagasaki (ORCID: https://orcid.org/0000-0002-4981-1715)
- Saori Kinjo
- Keisuke Nagasaki (ORCID: https://orcid.org/0000-0002-5882-661X)
- Maki Fukami (ORCID: https://orcid.org/0000-0001-9971-4035)
- Tomoe Ogawa
- Tatsuki Urakawa
- Shin‐ichiro Sano
Institutions
- St. Marianna University School of Medicine (JP)
- Hamamatsu University School of Medicine (JP)
- Okinawa Prefectural Chubu Hospital (JP)
- Dr Youth Clinic (KR)
- National Center For Child Health and Development (JP)
- Japanese Red Cross Society Wakayama Medical Center (JP)
- Shizuoka Children's Hospital (JP)
- Hamamatsu Medical Center (JP)
- Yamanashi Prefectural Central Hospital (JP)
- University of Toyama (JP)
- Nagasaki University (JP)
- University of Yamanashi (JP)
- Niigata University (JP)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2024-09-26
- DOI
- https://doi.org/10.1210/clinem/dgae666
- Citations
- 8
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 4.40
Funders
- Takeda Science Foundation
- National Center for Child Health and Development
- Japan Agency for Medical Research and Development
- Novo Nordisk Pharma
- Japan Society for the Promotion of Science