Genetic Study for Identifying Beta Thalassemia Trait in Relatives of Children with Beta Thalassemia Major
The beta thalassemia carrier rate was found to be highly prevalent among relatives of beta thalassemia major children. Despite the accuracy of gene screening in the detection of beta thalassemia carriers, the use of the most common 22 alleles can only detect 61.5% of carriers; hence, the value of tested gene study is still limited in the detection of carrier rates.
Authors
- Osama M. El-Asheer (ORCID: https://orcid.org/0000-0002-5844-5104)
- Dalia A. Nigm (ORCID: https://orcid.org/0000-0001-6587-2430)
- Mostafa Embaby (ORCID: https://orcid.org/0000-0002-9815-0239)
- Mohamed H Ghazally
- Mostafa S Khalaf
- Shimaa M Radi
Institutions
- Assiut University (EG)
Publication Details
- Journal
- Cureus
- Published
- 2024-09-26
- DOI
- https://doi.org/10.7759/cureus.70251
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00